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NLM Notice No. 75N97026Q00002 THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSALS. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS ARE NOT BEING REQUESTED. This notice is about the acquisition of commercial supplies and/or services for which the Government intends to negotiate with only one source. This acquisition will be processed under Revolutionary Far Overhaul (RFO) FAR Part 12.102(a) Restricting Competition; only one source is available. It is the intent of the National Institutes of Health (NIH), The National Library of Medicine (NLM), to negotiate on a sole-source basis with Next Move Software Ltd, Innovation Centre Unit 23, Science Park, Milton Road, Cambridge CB4 0EY UK, to provide one year of software support and maintenance for NextMove software. The Government requires software that can fully support PubChem, a National Center for Biotechnology Information (NCBI) database that manages complex chemically modified biomolecule data, including peptides, nucleic acids, oligosaccharides, glycoproteins, non-standard peptide analogues, and drug-antibody conjugates. This data must be accurately incorporated, managed, and updated in real-time to ensure the integrity of scientific information used by millions of researchers worldwide. The required software must interface seamlessly with PubChem's existing architecture, handle large volumes of data, support ongoing updates, and maintain security compliance. Only NextMove Software Limited develops and provides software with these specific capabilities, proprietary algorithms, and support infrastructure. Therefore, a sole source acquisition of NextMove Software is necessary to maintain operational continuity, data integrity, security, and the scientific utility of PubChem. No other software product currently available meets these unique Government requirements. The North American Industry Classification System Code (NAICS) is 513210 (Software Publishers), and the small business size standard is $47.0 million. NLM anticipates issuing a single, firm fixed price order. Interested Offerors may submit a capability statement not exceeding 5 pages in length which details their ability to satisfy this requirement. Quotes, capability statements, and related non-proprietary materials, or any questions must be submitted in writing by email to the Contracting Officer, Kathy.elliott@hhs.gov no later than 11:00 am Eastern Time on April 14, 2026. Reference: 75N97026Q00002 on all correspondence No collect calls or facsimile transmissions will be accepted. Any quotation received from an eligible offeror will be considered by the Government. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purpose of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. Disclaimer and Important Note…

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