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Combined Synopsis / Solicitation - Non-Competitive– Notice of Intent to Sole Source 1. SOLICITATION NUMBER: 75N98026Q00396 2. TITLE: Multi-dimensional sleep health and DNA methylation signatures 3. RESPONSE DATE: May 30, 2026, at 4:00 pm EST. 4. PRIMARY POINT OF CONTACT: Elaine Estrella Contract Specialist elaine.estrella@nih.gov Brian Lind Contract Specialist Brian.lind@nih.gov I. INTRODUCTION: This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N98026Q00396 and the solicitation is issued as a Notice of Intent (NOI) of a non-competitive (notice of intent) combined synopsis solicitation to award a contract or purchase order without providing for full or open competition (including brand-name). This acquisition is conducted under the authority of the FAR Part 12.603— Streamlined solicitation for commercial products or commercial services and is not expected to exceed the simplified acquisition threshold, and the authority of 41 U.S.C. 1901 and the statutory authority of FAR 6.302-3(a)(2)(ii). The National Institutes of Health (NIH) , Office of the Director (OD), Office of Acquisitions (OA), intends to negotiate and award a firm fixed price purchase order without providing for full and open competition (Including brand-name) to Brigham's Brigham and Women's Hospital (BWH) , 399 Revolution Drive Suite 735, Somerville, MA 02145 for a 3-month service continue and operationalize this existing project by retrieving the previously collected blood samples from the BWH Biorepository, processing them into aliquots, and shipping them to the National Institute on Aging (NIA) Laboratory of Neurogenetics for the planned assays. This requirement is a follow-on effort to prior research on population-based sleep health, NIA conducted a 14-night sleep study among approximately 1,000 participants in the Nurses' Health Study III using Fitbit devices, sleep diaries, and sleep questionnaires, and collected blood samples that were subsequently stored at the BWH Biorepository. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE and SET ASIDE STATUS NAICS code 541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) with a business size standard classification of 1000 employees. This acquisition is NOT set aside for small businesses. II. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01 III. STATUTORY AUTHORITY IV. DESCRIPTION OF REQUIREMENT: A. PURPOSE AND OBJECTIVES: The purpose of the present request is to continue and operationalize this existing project by retrieving the previously collected blood …

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• Attachment 1