Description

COMBINED SYNOPSIS / SOLICITATION-COMPETITIVE Title: Human putative humanin peptide (MT-RNR2) ELISA kits This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a separate written solicitation will not be issued. The solicitation number is 75N98026Q00243 and the solicitation is issued as request for quotation (RFQ) . Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. A fixed-price type of purchase order is contemplated for this requirement. The National Institute of Aging (NIA), Investigators in the HANDLS study require data on circulating humanin (MT-RNR2) levels to support an ongoing longitudinal study. This data will expand our current research on examining how circulating factors play a role in age-related chronic disease. Humanin has anti-apoptotic, metabolic and neuroprotective properties and also has been associated with lifespan. It is important to quantitatively measure serum levels of humanin in HANDLS participants to understand the role of this hormone in aging, and age-related chronic disease, including type 2 diabetes. The government requires specific ELISA kits because the government has specific expertise, equipment and resources to perform the work using these kits at our Institute. Attachment 1 – Purchase Description for additional details. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2025-05, dated 08-07-2025. The North American Industry Classification System (NAICS) Code for this procurement is 325414– Biological Product (Except Diagnostic) Manufacturing. Line Items: Through this procurement NIA anticipates a single award, firm fixed price purchase order for a total of forty-nine (49) Human Putative humanin peptide(MT-RNR2) ELISA Kits. (Lowest Price Technically Acceptable) as described in Attachment 1 – Purchase Description Below is a table that contains the line item numbers and description of the brand name or equal requirement for the anticipated award. Line No. Description 1 Human Putative humanin peptide(MT-RNR2) ELISA. SIZE 96T. QTY of 49. Description Requirement: Humanin (MT-RNR2) is a small, mitochondria-derived peptide that has attracted significant scientific interest due to its cytoprotective and anti-apoptotic properties. Humanin has been associated with aging and age-related chronic diseases including type 2 diabetes, neurodegenerative diseases and cardiovascular disease. To gain insight into its role in these processes in human cohorts, we will quantitatively measure levels of circulating humanin using ELISA kits. We will measure human humanin from serum from HANDLS participants. Serum samp…

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• Attachment 1