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PRE-SOLICITATION NON-COMPETITIVE – Notice of Intent to Sole Source SOLICITATION NUMBER: PCAS 02668 TITLE: CONSULTATION AND DATA STORAGE 26 000089 RESPONSE DATE: MAY 3, 2026, 09:00AM PRIMARY POINT OF CONTACT: VISHNUVAJJALA HANUMANTH RAO EMAIL: VISHNUH@MAIL.NIH.GOV INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Eye Institute (NEI), a part of the National Institutes of Health (NIH), intends to award a contract to Dr. Claire Marchal for the services required to analyze and integrate diverse molecular genomic data from human and mouse retinas. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE and SET ASIDE STATUS NAICS code 5413980 All Other Testing laboratory Services, and Technical Services with a business size standard classification of $19 Million This acquisition is NOT set aside for small businesses. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2024-07 dated 08-29-2024. This acquisition is conducted under the procedures as prescribed in FAR subpart 13.5—Simplified Procedures for Certain Commercial Items and FAR subpart 12—Acquisition of Commercial Items at an amount exceeding the SAT and not exceeding $7 million. STATUTORY AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the FAR Subpart 13.5—Simplified Procedures for Certain Commercial Items and the statutory authority of [specify the applicable authority: (1) FAR 6.302-1—Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 3304 (a)(1). DESCRIPTION OF REQUIREMENT: PURPOSE AND OBJECTIVES: PURPOSE: Precise gene expression patterns, which are critical for maintaining structure and function in the retinal cells, are controlled by regulatory networks that comprise of multiple levels including topology of the genome, regulatory sequences, transcription factors and signaling proteins. Next generation sequencing methods have now made it possible to perform genome-wide studies of gene expression, genetic variations and corresponding regulatory proteins. We are interested in elucidating the nature of gene regulatory networks during development and how these are disrupted in aging and disease to help us design novel treatment paradigms for blinding largely incurable retinal and macular degenerative diseases. A major goal of our research is to integrate diverse molecular genomic datasets on genome-wide gene expression with regulatory factor binding, topological information and other changes in the retina during normal development, aging and disease conditions in humans and mice. These networks will be used to explore genomic regulations in the retina and understand the effect of human genetic generations that are associated with retinal and macu…
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