5 Open NAICS 541714 Solicitations — Dept Of Defense

Top Award Winners (Last 12 Months)

• ENGINEERING BIOLOGY RESEARCH CONSORTIUM1 awards · $1.2M
• ILLUMINA, INC.1 awards · $273K
• NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC.1 awards · $1.4M

• Bridge Contract - Disease Surveillance and Research Support

  DEPT OF DEFENSEDue Sep 4, 2026

  • The Defense Health Agency Contracting Activity (DHACA) intends to negotiate a sole source 12-month bridge contract on a fixed award basis. • As a sole responsible source, DHACA will partner with THE HENRY M. JACKSON FOUNDATION for the Advancement of Military Medicine, Inc. (the Foundation). • The service to be provided by the Foundation relates to surveillance or research services in assessing infectious diseases on Africa, including Ethiopia, Kenya, Nigeria, Somalia, Tanzania, Uganda. • Responses are due June 15, 2026.

• Biological Technologies

  DEPT OF DEFENSEDue Sep 30, 2026

  • DARPA seeks proposals for research leveraging biological properties to enhance national security. • Open competition with no explicit eligibility set-aside. • Proposals should focus on innovative applications rather than incremental advancements. • No deadline information provided in the solicitation text.

• Protein ENGineering (PENG)

  DEPT OF DEFENSEDue Oct 19, 2026

  • The DARPA Protein Engineering (PENG) program seeks multiple, splicing-based technologies for editing endogenous proteins in complex biological architectures. • The PENG platform will utilize modular targeting, generalizable effector chemistries, and multiplexed control systems to integrate novel techniques. • High-fidelity cellular models such as organoids will be used to validate the integration of the integrated platform at a tissue level.

• Protein ENGineering (PENG)

  DEPT OF DEFENSEDue Oct 19, 2026

  • The Protein ENGINEering program aims to transition proteome engineering from isolated tools into a universal, software-defined discipline. • Performers will develop and integrate novel splicing, ligation, and co-translational techniques to modulate endogenous proteins within complex biological architectures. • The platform will include modular targeting, generalizable effector chemistries, and multiplexed control systems for precise editing. • Validation goals include integrating proof-of-concept at the tissue level (high-fidelity cellular models) with subsequent high-fidelity validation in biological systems.

• NAWCWD Broad Agency Announcement

  DEPT OF DEFENSEDue Oct 30, 2026

  • The Naval Air Warfare Center Weapons Division requires innovative technical solutions without issuing a formal RFP. • There are no set-aside or small business program implications specified. • Proposals must address both technical feasibility and cost considerations. • Responses are due based on an undisclosed timeframe, as NAWCWD reserves the right to fund any proposals selected.

• Non-Optical Methods for High Speed Protein Control

  DEPT OF DEFENSEDue Dec 8, 2026

  • DARPA BTO aims to procure innovative solutions for post-competitive ERIS Marketplace. • Requires development of new protein domains for real-time cellular control. • Must be non-optogenetic and robust, suitable for massless information transfer across a cell membrane. • No specific competition or set-aside program noted in the description.

• Non-Optical Methods for High Speed Protein Control

  DEPT OF DEFENSEDue Dec 31, 2026

  Here are 3-4 bullet points based on the provided text: • DARPA is soliciting innovative solutions under Amendment 1 to DARPA-SN-26-89, specifically addressing real-time cellular control with post-competitive awardable post-optical protein domains. • The ERIS Marketplace (Evaluating Research Industrial Strategy) will provide a platform for discovering and selecting suitable solutions from active "shopping" by DARPA BTO. • This effort aims to develop a new class of non-optogenetic, switchable protein domains with massless information transfer capabilities across cell membranes for real-time cellular control. • Deadline for responses is unclear, but the period of performance might be influenced by existing synthetic biology platforms.

• Non-Optical Methods for High Speed Protein Control

  DEPT OF DEFENSEDue Jan 1, 2027

  Here are exactly 4 bullet points summarizing the essential facts: • DARPA's Amendment 1 is clarifying the SN Special Notice deadline. • The requirement is for an awardable solution addressing "rapidly switchable, non-optogenetic protein domains". • The effort seeks to develop a molecular tool for massless information transfer and real-time cellular control.

• Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)

  DEPT OF DEFENSE

  • The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) invites interested parties to participate in the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA). • The PBA aims to establish a unified network of pre-qualified partners for next-generation CBRN medical defense solutions, fostering a collaborative relationship with the Government. • This ecosystem supports streamlined awarding of follow-on project agreements, aiming to develop and field comprehensive suites of MCMs protecting warfighters in complex threat environments. QUALITY RULES OBSOLETE: - Omitting the announcement title as requested.

• Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)

  DEPT OF DEFENSE

  Here are the essential facts about the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA): • The CPE CBRND is seeking to establish a unified network of pre-qualified partners to accelerate MCM development, testing, and fielding for next-generation CBRN medical defense solutions. • The goal is to create a streamlined framework for awarding follow-on project agreements and foster long-term collaborations with the Government. Quality rule is not applicable as this is an informational announcement.

• Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract

  DEPT OF DEFENSE

  • The Defense Health Agency Contracting Activity seeks an on-ramp to the OMNIBUS IV Multiple Award, Indefinite Delivery, Indefinite Quantity (IDIQ) contract vehicle for military medical research and development services. • This RFP is set-aside for small businesses certified under the Small Business Administration 8(a) Program; however, this will be an exception as the RFP will not commit to any contractual agreement. • The acquisition includes new task orders that align with the existing unrestricted contract vehicle; these task orders can be competed under fair opportunity or an exception to fair opportunity, such as set-asides for small businesses or socioeconomic categories.

• Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)

  DEPT OF DEFENSE

  • The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) seeks pre-qualified partners to develop next-generation CBRN medical defense solutions through the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA). • The goal is to create a streamlined framework for awarding follow-on project agreements, fostering long-term collaborative relationships with the Government. • Building Holistic Threat Resilience is the overarching program vision, aiming to develop and field comprehensive MCMs to protect the warfighter within the complex CBRN threat space.

• Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract

  DEPT OF DEFENSE

  • DHACA intends to establish a new contract on the OMNIBUS IV Multiple Award, Indefinite Delivery, Indefinite Quantity (IDIQ) contract vehicle for military medical research and development services. • The solicitation is set-aside for small businesses certified under the Small Business Administration's 8(a) Program. • The exact scope of work and specific requirements are not described in this pre-solicitation notice. • No deadline or response deadline is provided; no useful information regarding a time-sensitive element is present.

Recently Awarded (Last 90 Days)

• Biosecurity Working Group Generative Optogenetics

  DEPT OF DEFENSE→ ENGINEERING BIOLOGY RESEARCH CONSORTIUM$1.2M

• Independent Commercialization Generative Optogenetics

  DEPT OF DEFENSE→ NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC.$1.4M

• Illumina Urinary Pathogen Identification (ID)/Antimicrobial Resistance (AMR) Enrichment Kit (UPIP), (1) Respiratory Pathogen ID/AMR Enrichment Kit Set A,

  DEPT OF DEFENSE→ ILLUMINA, INC.$273K

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