15 Open NAICS 541714 Solicitations — Dept Of Defense
15 open NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)) solicitations are currently posted by Dept Of Defense. Over the past 12 months, 23 solicitations were posted in this category.
Top Award Winners (Last 12 Months)
- ENGINEERING BIOLOGY RESEARCH CONSORTIUM1 awards · $1.2M
- ILLUMINA, INC.1 awards · $273K
- NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC.1 awards · $1.4M
Open Solicitations
See all →- Sepsis Research Blood Sample Collection Services
DEPT OF DEFENSEDue Oct 15, 2026
• WRAIR requires sepsis research blood sample collection services including longitudinal clinical data. • This is a sole source extension to Medstar Health Research Institute under NAICS 541714. • Samples must be from septic and non-septic burn patients for biomarker assessment and SeptiBurnAlert refinement. • Extension is intended as a cost R&D contract under FAR 6.103-1 due to non-commercially available sources.
- Protein ENGineering (PENG)
DEPT OF DEFENSEDue Oct 19, 2026
• The Protein ENGINEering program aims to transition proteome engineering from isolated tools into a universal, software-defined discipline. • Performers will develop and integrate novel splicing, ligation, and co-translational techniques to modulate endogenous proteins within complex biological architectures. • The platform will include modular targeting, generalizable effector chemistries, and multiplexed control systems for precise editing. • Validation goals include integrating proof-of-concept at the tissue level (high-fidelity cellular models) with subsequent high-fidelity validation in biological systems.
- Protein ENGineering (PENG)
DEPT OF DEFENSEDue Oct 19, 2026
• The DARPA Protein Engineering (PENG) program seeks multiple, splicing-based technologies for editing endogenous proteins in complex biological architectures. • The PENG platform will utilize modular targeting, generalizable effector chemistries, and multiplexed control systems to integrate novel techniques. • High-fidelity cellular models such as organoids will be used to validate the integration of the integrated platform at a tissue level.
- NAWCWD Broad Agency Announcement
DEPT OF DEFENSEDue Oct 30, 2026
• The Naval Air Warfare Center Weapons Division requires innovative technical solutions without issuing a formal RFP. • There are no set-aside or small business program implications specified. • Proposals must address both technical feasibility and cost considerations. • Responses are due based on an undisclosed timeframe, as NAWCWD reserves the right to fund any proposals selected.
- Non-Optical Methods for High Speed Protein Control
DEPT OF DEFENSEDue Dec 8, 2026
• DARPA BTO aims to procure innovative solutions for post-competitive ERIS Marketplace. • Requires development of new protein domains for real-time cellular control. • Must be non-optogenetic and robust, suitable for massless information transfer across a cell membrane. • No specific competition or set-aside program noted in the description.
- Non-Optical Methods for High Speed Protein Control
DEPT OF DEFENSEDue Dec 31, 2026
Here are 3-4 bullet points based on the provided text: • DARPA is soliciting innovative solutions under Amendment 1 to DARPA-SN-26-89, specifically addressing real-time cellular control with post-competitive awardable post-optical protein domains. • The ERIS Marketplace (Evaluating Research Industrial Strategy) will provide a platform for discovering and selecting suitable solutions from active "shopping" by DARPA BTO. • This effort aims to develop a new class of non-optogenetic, switchable protein domains with massless information transfer capabilities across cell membranes for real-time cellular control. • Deadline for responses is unclear, but the period of performance might be influenced by existing synthetic biology platforms.
- Non-Optical Methods for High Speed Protein Control
DEPT OF DEFENSEDue Jan 1, 2027
Here are exactly 4 bullet points summarizing the essential facts: • DARPA's Amendment 1 is clarifying the SN Special Notice deadline. • The requirement is for an awardable solution addressing "rapidly switchable, non-optogenetic protein domains". • The effort seeks to develop a molecular tool for massless information transfer and real-time cellular control.
- BROAD AGENCY ANNOUNCEMENT - BIOMEDICAL RESEARCH AND DIVING EQUIPMENT DEVELOPMENT
DEPT OF DEFENSEDue Nov 30, 2027
• Navy seeks biomedical research and diving equipment development for diver health, safety, and effectiveness. • This is an unrestricted competition, open to all qualified offerors, with a focus on innovative solutions. • Projects should focus on rapid transition to fleet capabilities, with typical project duration of two years or less. • Pre-proposals and full proposals will be accepted over a two-year period, with awards to be made in FY 2028 and 2029.
- Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)
• The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) seeks pre-qualified partners to develop next-generation CBRN medical defense solutions through the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA). • The goal is to create a streamlined framework for awarding follow-on project agreements, fostering long-term collaborative relationships with the Government. • Building Holistic Threat Resilience is the overarching program vision, aiming to develop and field comprehensive MCMs to protect the warfighter within the complex CBRN threat space.
- Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)
• The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) invites interested parties to participate in the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA). • The PBA aims to establish a unified network of pre-qualified partners for next-generation CBRN medical defense solutions, fostering a collaborative relationship with the Government. • This ecosystem supports streamlined awarding of follow-on project agreements, aiming to develop and field comprehensive suites of MCMs protecting warfighters in complex threat environments. QUALITY RULES OBSOLETE: - Omitting the announcement title as requested.
- Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract
• The Defense Health Agency Contracting Activity seeks an on-ramp to the OMNIBUS IV Multiple Award, Indefinite Delivery, Indefinite Quantity (IDIQ) contract vehicle for military medical research and development services. • This RFP is set-aside for small businesses certified under the Small Business Administration 8(a) Program; however, this will be an exception as the RFP will not commit to any contractual agreement. • The acquisition includes new task orders that align with the existing unrestricted contract vehicle; these task orders can be competed under fair opportunity or an exception to fair opportunity, such as set-asides for small businesses or socioeconomic categories.
- Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)
Here are the essential facts about the CBRN Medical Countermeasure (MCM) Participant Basic Agreement (PBA): • The CPE CBRND is seeking to establish a unified network of pre-qualified partners to accelerate MCM development, testing, and fielding for next-generation CBRN medical defense solutions. • The goal is to create a streamlined framework for awarding follow-on project agreements and foster long-term collaborations with the Government. Quality rule is not applicable as this is an informational announcement.
- Trusted Partner Program Coming Soon - Update
• The Army plans to solicit for an unspecified requirement under Solicitation W911NF-26-R-A009. • This solicitation is on hold pending a review of Army priorities, which may lead to RFP updates. • Interested parties must monitor sam.gov for the official announcement and updates.
- Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract
• The notice directs viewers to a different Notice ID number for the OMNIBUS IV on-ramp solicitation. • The original Notice ID# HT942626RE002 is no longer valid for this solicitation. • Viewers should refer to Notice ID# HT942627RE002 for the correct information. • No additional amendments will be issued under the original Notice ID.
- Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract
• DHACA seeks on-ramp proposals for OMNIBUS IV IDIQ contract covering military medical research and development services. • The RFP will be set-aside for small businesses certified under the Small Business Administration 8(a) Program. • The contract vehicle has a base ordering period through 19 June 2027 and an Option Ordering Period through 19 June 2032. • The RFP is expected to be posted by early November 2026.
Frequently Asked Questions
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