This is a Notice of Intent, not a request for quotation. No solicitation will be issued, and no quotations will be requested. The Department of Health and Human Services, on behalf of the National Institutes of Health (NIH), National Human Genome Research Institute (NHGRI), intends to award a firm-fixed-price purchase order to QIAGEN for the renewal of the QIAGEN Human Gene Mutation Database Professional License – MySQL Software Renewal, Catalog No. 834080, for a 12-month period of performance. The purpose of this requirement is to renew NHGRI's QIAGEN Human Gene Mutation Database (HGMD) Professional MySQL software license for a 12-month period of performance. The HGMD license is a mutation visualization software tool that provides a graphical representation of variants along aligned DNA and protein sequences, which can then be exported for further analysis. The database contains mutation support and sequence-specific details necessary for patient disease identification and analysis in the Undiagnosed Diseases Program (UDP). The requirement includes the following QIAGEN product: QIAGEN Human Gene Mutation Database Professional License – MySQL Software Renewal Catalog No.: 834080 Quantity: 1 Period of Performance: 12 months