SOURCES SOUGHT NOTICE The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), is seeking capability statements from Small Business organizations to provide the Government a resource that can maintain the NIH Brain Development Cohorts (NBDC) Biobank, a repository to process, store, analyze, and distribute de-identified biological samples and related data from the Adolescent Brain Cognitive DevelopmentSM (ABCD) Study and HEALthy Brain and Child Development (HBCD) Study. This is a SMALL BUSINESS SOURCES SOUGHT NOTICE to determine the availability of ALL small businesses (e.g., 8(a), Veteran-owned small businesses, service-disabled Veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses, and women-owned small businesses) with the capability to maintain the NBDC Biobank. Capable Vendors must demonstrate the experience and capability necessary to manage a large biobank containing over 550,000 samples, which would be transferred at the outset of the award, if other than the incumbent. Capable Vendors must demonstrate the ability to receive a volume of approximately 170,000 samples over the course of the contract. Interested small business organization must demonstrate the experience, capabilities, and possess in-depth knowledge in the areas listed below. Sample and Data Management Demonstrate an ability to safely process, store, and track between 500,000-700,000 biospecimen samples from a wide range of biospecimen types (e.g. blood, serum, plasma, DNA, RNA, saliva, hair, urine, teeth, fecal matter, placenta, umbilical cord blood and tissue) at a variety of storage conditions, and perform expert quality control and assurance procedures; Provide 48 research sites across the country with collection kits including barcoded tubes with human readable labels for the collection of biospecimens which will be registered and tracked in the Contractor's auditable Laboratory Information Management System (LIMS). Provide site coordinators and research staff with training for ordering supplies and collecting samples; Maintain positive chain of custody and resolve data/sample discrepancies (e.g. missing data, incorrect information, samples sent to the wrong location) through management and support of issue tracking and resolution. This involves coordination with sites, site monitors, study staff, and the respective receiving or data management teams at the Biobank. Centrally manage and effectively distribute biosamples in the repository to qualified investigators approved through the Biospecimens Access Programs in a cost-effective manner; Technical & Informatics Requirements Maintain and update databases linking phenotypic/genotypic information with participant and sample IDs; Manage and enhance the NBDC Biobank portal (both front-end and back-end) to support all currently available features and provide updates and improvements when requested. Requirements include, but are not limited to: Maintain …