CVM possesses significant bioinformatics expertise; however, personnel with the specific skills to perform these tasks are currently allocated to other high-priority agency projects. To meet the urgent timelines for this analysis, CVM requires external, focused support to perform the necessary visual validation of swine variants from an already generated list of candidate variants and the generation of CRISPRme input files for cattle, chicken, and swine. This approach will allow the project to proceed efficiently while enabling CVM's internal experts to provide oversight and ensure the validated variants and CRISPRme input files meet their precise scientific requirements. Please see attached RFQ.