Dynamic Light Scattering Instrument Upgradeview on SAM.gov

Title: Dynamic Light Scattering Instrument Upgrade Solicitation No.: 75N98026Q01220 This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued. The solicitation number is 75N98026Q01220 . This solicitation is issued as a Notice of Intent (NOI) for a non-competitive acquisition and is intended to result in the award of a purchase order without providing for full and open competition. This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services . The statutory authority for this non-competitive acquisition is 41 U.S.C. 1901 , as implemented by FAR 6.302-3(a)(2)(ii) , as applicable. The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions , intends to negotiate and award a Firm-Fixed-Price Purchase Order on a non-competitive basis to: Waters Technologies Corporation 34 Maple Street Milford, MA 01757 for a Wyatt Systems DynaPro NanoStar II and associated upgrade/configuration, accessories, standards, installation, training, and technical support. DESCRIPTION OF REQUIREMENT The purpose of this acquisition is to replace an aging and failing dynamic light scattering (DLS) instrument currently used by the NIH laboratory. The existing Wyatt DLS instrument is approximately 16 years old and is well beyond its expected service life. In addition, degradation of the instrument's laser has significantly reduced its performance and rendered it unsuitable for many protein samples. The Government requires a replacement system that provides reliable, high-sensitivity dynamic light scattering measurements while maintaining compatibility with the laboratory's existing Wyatt Systems infrastructure, workflows, and applications. The proposed Wyatt Systems DynaPro NanoStar II provides combined Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) capabilities. These complementary measurements provide information regarding particle size and molecular mass and will support characterization of protein complexes and higher-order assemblies relevant to ongoing NIH research involving viral nucleocapsid proteins and other biomolecular systems. The system's broad measurement range, wide temperature range, small-volume sample capability, and rapid, non-destructive measurements are particularly important for research involving limited quantities of protein or samples that are difficult to produce. The ability to perform measurements using small sample volumes will help conserve valuable research materials and facilitate routine sample characterization. The replacement instrument will also support collaborative research projects by providing an accessible and standardized m…