NON-COMPETITIVE COMBINED SYNOPSIS / SOLICITATION Title: Annual Service and Maintenance Agreement for Thermo Scientific Quadrupole-Orbitrap Hybrid w/IC (Exploris 480) mass spectrometer and associated Vanquish components. (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued. (ii) The solicitation number is 75N98026Q00475. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive combined synopsis/solicitation to award a contract or purchase order without providing for full and open competition (including brand-name, if applicable). This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services , and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii). The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed-Price on a non-competitive basis to THERMO ELECTRON NORTH AMERICA LLC 1400 Northpoint PKWY STE 10 West Palm Beach, Florida 33407-1976, United States The Thermo Electron North America LLC, as the Original Equipment Manufacturer (OEM) of the Thermo Scientific Exploris 480 mass spectrometer and associated Vanquish liquid chromatography modules, is the only source capable of providing comprehensive manufacturer-certified support for the fully integrated analytical system. The Exploris 480 mass spectrometer is a highly specialized and proprietary instrument that requires OEM-trained and certified service engineers with direct access to proprietary diagnostic tools, firmware, software, replacement parts, and technical documentation. The associated Vanquish liquid chromatography modules operate as integrated components of the overall analytical platform and require coordinated manufacturer-level support to ensure system compatibility, validated performance, and proper communication between all modules. Although third-party vendors may be able to perform limited maintenance on certain liquid chromatography components, they cannot provide complete integrated system-level support for the Exploris 480 platform. Non-OEM servicing may result in delays obtaining proprietary replacement parts, incompatibility issues, inability to perform manufacturer-authorized software or firmware updates, and potential degradation of instrument performance. In addition, Thermo Fisher Scientific does not guarantee system performance or assume liability for failures resulting from unauthorized third-party servicing. Use of non-OEM support could compromise instrument reliability, increase downtime, and negatively impact ongoing scientific studies. The ma…