NOTICE OF INTENT TO SOLE SOURCE The Department of Veterans Affairs, Network Contracting Office (NCO) 22, located at 4811 Airport Plaza Drive, Long Beach, CA 90815 is issuing this Notice of Intent (NOI) to inform industry contractors of the Government s intent to execute a firm fixed price, Sole Source Award. The intended Contractor is a small vendor Applied Spectral Imaging Inc. located at 6160 Innovation Way, Carlsbad, CA 92009. The VA Greater Los Angeles Healthcare System Cytogenetics Laboratory requires a software and hardware upgrade to its existing Applied Spectral Imaging (ASI) GenASIs imaging systems to add automated (Aided) Karyotyping capability. The upgrade adds ASI s Aided Karyotyping software licenses, which provide automatic chromosome segmentation and classification, together with the GenASIs version 8.0 software update and the supporting hardware (high-end PCs, NVIDIA T1000 8GB graphics cards, and memory upgrades) required to run it, plus a Gen 2 stage controller and on-site installation and calibration. The upgrade covers six existing installed systems: two 9-slide scanning platforms (S/N SC230006 and SC160015), three capture stations (S/N FV110030, ASIINC0045, and BV240012), and one review station (S/N RV160046). The upgraded systems will be used in the clinical Cytogenetics Laboratory to perform automated metaphase karyotype analysis on patient specimens, reducing manual analysis time, standardizing karyotype interpretation, and improving turnaround time for chromosome studies that support Veteran diagnostic care. Applied Spectral Imaging, Inc. (ASI) is the Original Equipment Manufacturer (OEM) and the sole developer, owner, and licensor of the proprietary GenASIs imaging platform and the Aided Karyotyping software module. This requirement is not the purchase of a new, stand-alone karyotyping system; it is an upgrade to the laboratory s six existing, ASI-manufactured GenASIs systems that are already installed and in clinical production use. The following characteristics limit availability to ASI as the only source: Proprietary software and hardware. The Aided Karyotyping license, the GenASIs version 8.0 software update, and the matched hardware upgrades are proprietary to ASI and can only be licensed, installed, and integrated on ASI s own GenASIs systems. No other vendor can provide, install, or integrate this software on ASI equipment. Native integration with the installed base. The upgrade must operate on the laboratory s existing installed ASI scanning, capture, and review stations without replacing the installed microscopes, cameras, and imaging hardware. No competing product performs automatic chromosome segmentation and classification directly on the installed ASI GenASIs platform. Active Platinum Service Contract and warranty integrity. The systems are covered under an active ASI Platinum Service Contract, and the quoted upgrade pricing and discounts are tied to that contract. Only the OEM can perform these software and …