High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)view on SAM.gov

DEPT OF DEFENSE › DEF ADVANCED RESEARCH PROJECTS AGCY

Posted Oct 28, 2026

Due Nov 5, 2026

NAICS 541714 – Research and Development in Biotechnology (except Nanobiotechnology)

Sol # DARPA-PA-27-01

AI Summary

• DARPA seeks proposals for an in-silico capability to map all protein-protein interactions.
• This solicitation is unrestricted and open to all eligible offerors.
• The capability must demonstrate utility in identifying targets for traumatic brain injury diagnosis and treatment.
• No deadline for proposals is specified in the update.

Description

UPDATE: The purpose of Amendment 1 to DARPA-PA-27-01, the HUBBLE Program Announcement (PA), is to update Attachment B and the verbiage in Section 4.1.2 and Section 7.8 of the Program Announcement. The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.

Classification

NAICS541714

PSC CodeAC12

Contracting Office

OfficeDEF ADVANCED RESEARCH PROJECTS AGCY

CityARLINGTON

StateVA

ZIP222032114

Contacts

Dr. Abhishek Singharoy, DARPA/BTO

HUBBLE@darpa.mil

Attachments (8)

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