PRE-SOLICITATION NOTICE: The VA National Acquisition Center intends to issue a Request for Proposal (RFP) 36E79726R0024 for an unrestricted procurement for Fluorouracil 5% Cream for the Department of Veterans Affairs (VA), Department of Defense (DOD), Bureau of Prisons (BOP), and Indian Health Service (IHS). The VA will award one contract to the responsible offeror who will be able to provide an uninterrupted source of supply for the contracted items. The contract period will be for one year plus four pre-priced one-year option periods. The contract items will be distributed through the VA s and DOD s respective Pharmaceutical Prime Vendor Programs. Offerors must state the exact name (name that appears on label) by which the drug will be supplied and have a unique NDC number. Glass bottles are not acceptable. Solicitation # 36E79726R0024 will be electronically issued in commercial item format in accordance with FAR Part 12 on or about 06/08/2026 with a tentative closing date of 06/22/2026. The NAICS code for this procurement is 325412. Any future amendments and other miscellaneous documents will be available electronically for download at the following URL: http://www.sam.gov. No paper copies of the solicitation will be available, and no telephone requests for paper copies of the solicitation will be accepted. Interested offerors are advised to continuously check this URL for any changes to this solicitation. All responsible sources may submit an offer that if timely received, will be considered. The point of contact for this procurement is Amber Zavala. Questions can be e-mailed to: amber.zavala@va.gov. The estimated annual requirements are as follows: Description Size Estimated Annual Requirements FLUOROURACIL 5% CREAM,TOP 40(grams) 126,107 (tubes)