This is strictly a request for information. The Government has no obligation for award. If interested, please provide a capabilities statement. The Contractor shall provide the infrastructure, personnel, training, materials, foods, supplies, and operational support necessary to investigate the physiological, cognitive, and clinical effects of mild hypobaric hypoxia to inform vehicle atmospheric conditions for NASA's Artemis Program. The objective of the multiple-day testing is to characterize acute responses and the time course of acclimation using clinical and physiological measurements in participants who are housed continuously for 7 days in the chamber. The data from these studies will be included in a larger data set for the development of the Aerospace Estimation Tool for Hypobaric Exposure Risk (AETHER). RFI responders are to provide capabilities to perform blood/saliva analysis.If processing of blood/saliva cannot be completed at the chamber facility, include costs to ship samples to JSC for processing as part of this Optional work.Budget is firm fixed price. Budget quotes can include payments for interim milestone completion. Dates for each interim milestone should be set by the supplier.