The U.S. Food and Drug Administration (FDA), Office of Acquisitions and Grants Services (OAGS), is issuing Solicitation 75F40126R00049 for the IRV Lab Exhaust & Vacuum Pump Replacement Project at the FDA Pacific Southwest Laboratory, 19701 Fairchild Road, Irvine, California. This is a full and open competition . The contractor shall provide all labor, materials, equipment, supervision, permits, testing, commissioning, and related services needed to remove and replace the laboratory vacuum pump system and install a new laboratory exhaust system. The work also includes Building Automation System (BAS) integration, testing and balancing (TAB), commissioning, training, and project closeout, as described in the solicitation and Scope of Work. Mandatory Site Visit: A mandatory site visit will be held on: Date: Wednesday, July 22, 2026 Time: 8:30 a.m. Pacific Time Location: FDA Pacific Southwest Laboratory, 19701 Fairchild Road, Irvine, CA 92612 To attend, offerors must register by 12:00 p.m. Pacific Time on Monday, July 20, 2026 by emailing the Contracting Officer and Contract Specialist listed in the solicitation. Include the names of all attendees when registering. Each company may send up to three (3) representatives. All attendees must present a valid government-issued photo ID and comply with FDA security requirements. Attendance at the site visit is required. The Government will not consider proposals from offerors that do not attend the mandatory site visit. No exceptions. Submit questions and proposals by the deadlines shown in the solicitation. The solicitation, attachments, and any amendments are available through this SAM.gov notice. Offerors must have an active registration in SAM.gov when they submit a proposal, during the evaluation period, and before contract award.