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Description
The National Institute of Neurological Disorders and Stroke (NINDS), Neurodegenerative Diseases Research Section (NDRS), requires a 12-month subscription/access to the Illumina DRAGEN GCP Level 4 platform to process approximately 1,300,000 GB of whole-genome sequencing data derived from 10,000 human genomes. The platform must support graph-based alignment to the human reference genome (hg38), accurate variant calling, and detection of single-nucleotide variants, insertions/deletions, structural variants, copy number variants, and repeat expansions. The platform must be fully compatible with Illumina-generated sequencing data and existing DRAGEN-processed datasets. The contractor shall provide access and operational availability of the DRAGEN GCP platform and processing capability sufficient to analyze the 10,000 genomes during the 12-month period of performance.
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