This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Part 12. This announcement constitutes the only solicitation. Quotations are being requested and a separate written solicitation will not be issued. Solicitation number 12639526Q0181 is issued as a Request for Quotation (RFQ) for Temperature-controlled Courier Services. This acquisition is set-aside for small business concerns. The applicable North American Industry Classification Standard Code is 492110 The small business size standard is 1,500 employees. This acquisition is a Total Small Business Set-Aside. All responsible sources may submit a quotation which will be considered by the agency. See attached documents for performance details, metrics, and solicitation instructions. Offers which do not conform to the guidance set forth in the attached documents will be determined to be nonresponsive.