This Broad Agency Announcement (BAA) seeks the best RDT&E approaches to meet various technology objectives of Air Force Technical Application Center (AFTAC). The Government encourages proposals that span a wide spectrum of possible technical and business solutions in response to the specific technology topics stated in Attachment 6. The Government reserves the right to award funding to any combination of proposals which offer the best overall value to the Government, and to oversee any and all processes and approaches once initiated. Awards of efforts as a result of this announcement will be in the form of contracts or other transactions (OT) as codified in 10 U.S.C. §2371b (section 2371b). AFTAC is looking for new capabilities in nuclear treaty monitoring, advanced detection technologies to support the counter-proliferation of weapons of mass destruction and other applied technologies. TOPICS: AFTAC-001, GEOPHYSICS AND SEISMOLOGY AFTAC-002, ATMOSPHERE AND SPACE AFTAC-003, DIRECTED ENEGRY WEAPON (DEW) AFTAC-004, NUCLEAR AND NUCLEAR-RELATED MATERIALS ANALYSIS AFTAC-005, MATERIALS MODELING AND ANALYSIS AFTAC-006, ENTERPRISE WIDE INTEGRATION AND ARCHITECTURE MODERNIZATION AFTAC-007, ENTERPRISE ASSET AND LIFECYCLE MANAGEMENT IMPROVEMENTS AFTAC-008, HIGH PERFORMANCE AND SECURE CLOUD COMPUTING AND DEV OPS SOLUTIONS FOR DATA INGESTION, EXPLOITATION, AND DISSEMINATION This is a follow-on solicitation to AFTAC_BAA_2023