This Commercial Solutions Opening (CSO), as contemplated in Federal Acquisition Regulation (FAR) 6.102(b)(c)(d) and Class Deviation 2022-O0007 – Defense Commercial Solutions Opening, is a competitive solicitation of proposals focused on technologies to meet the Air Force Technical Application Center's (AFTAC) mission. AFTAC is looking for new capabilities in nuclear treaty monitoring, advanced detection technologies to support the counter-proliferation of weapons of mass destruction and other applied technologies. AFTAC seeks the best approaches to meet the technology objectives within the capability areas listed below. Detailed topics associated with each capability area appear in Attachment 6. TOPIC: AFTAC-001, GEOPHYSICS AND SEISMOLOGY AFTAC-002, ATMOSPHERE AND SPACE AFTAC-003, DIRECTED ENEGRY WEAPON (DEW) AFTAC-004, NUCLEAR AND NUCLEAR-RELATED MATERIALS ANALYSIS AFTAC-005, MATERIALS MODELING AND ANALYSIS AFTAC-006, ENTERPRISE WIDE INTEGRATION AND ARCHITECTURE MODERNIZATION AFTAC-007, ENTERPRISE ASSET AND LIFECYCLE MANAGEMENT IMPROVEMENTS AFTAC-008, HIGH PERFORMANCE AND SECURE CLOUD COMPUTING AND DEV OPS SOLUTIONS FOR DATA INGESTION, EXPLOITATION, AND DISSEMINATION This is a follow-on solicitation to AFTAC_CSO_2023